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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2007 2
2008 1
2009 2
2010 3
2011 5
2012 4
2013 3
2014 2
2015 2
2016 2
2017 10
2018 7
2019 7
2020 6
2021 5
2022 11
2023 11
2024 4

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76 results

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Page 1
Genetics of ovarian insufficiency and defects of folliculogenesis.
França MM, Mendonca BB. França MM, et al. Best Pract Res Clin Endocrinol Metab. 2022 Jan;36(1):101594. doi: 10.1016/j.beem.2021.101594. Epub 2021 Oct 14. Best Pract Res Clin Endocrinol Metab. 2022. PMID: 34794894 Review.
Thirty-four of these genes (AARS2, AIRE, ANTXR1, ATM, BMPR1B, CLPP, CYP17A1, CYP19A1, DCAF17, EIF2B, ERAL1, FANCA, FANCC, FMR1, FOXL2, GALT, GNAS, HARS2, HSD17B4, LARS2, LMNA, MGME1, NBN, PMM2, POLG, PREPL, RCBTB1, RECQL2/3/4, STAR, TWNK, and XRCC4/9) have been link …
Thirty-four of these genes (AARS2, AIRE, ANTXR1, ATM, BMPR1B, CLPP, CYP17A1, CYP19A1, DCAF17, EIF2B, ERAL1, FANCA, FANCC, FMR1, FO …
ERK1/2-SOX9/FOXL2 axis regulates ovarian steroidogenesis and favors the follicular-luteal transition.
Baddela VS, Michaelis M, Tao X, Koczan D, Vanselow J. Baddela VS, et al. Life Sci Alliance. 2023 Aug 2;6(10):e202302100. doi: 10.26508/lsa.202302100. Print 2023 Oct. Life Sci Alliance. 2023. PMID: 37532283 Free PMC article.
Interestingly, the incidence of SOX9 is largely uncovered in ovarian cells and is found to regulate FOXL2 along with CYP19A1 and STAR genes, encoding rate-limiting enzymes of steroidogenesis, in cultured granulosa cells. We propose that the novel ERK1/2-SOX9/FOXL …
Interestingly, the incidence of SOX9 is largely uncovered in ovarian cells and is found to regulate FOXL2 along with CYP19A1 a …
Identification of SF-1 and FOXL2 and Their Effect on Activating P450 Aromatase Transcription via Specific Binding to the Promoter Motifs in Sex Reversing Cheilinus undulatus.
Ji X, Bu S, Zhu Y, Wang Y, Wen X, Song F, Luo J. Ji X, et al. Front Endocrinol (Lausanne). 2022 May 10;13:863360. doi: 10.3389/fendo.2022.863360. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35620392 Free PMC article.
In vitro transfection assays showed that SF-1 could upregulate cyp19a1 promoter activities, but FOXL2 could only enhance cyp19a1b promoter transcriptional activity in the HEK293T cell line. ...Collectively, these results suggest that both FOXL2 and SF-1 are i …
In vitro transfection assays showed that SF-1 could upregulate cyp19a1 promoter activities, but FOXL2 could only enhance cyp19 …
Sex-specific dmrt1 and cyp19a1 methylation and alternative splicing in gonads of the protandrous hermaphrodite barramundi.
Domingos JA, Budd AM, Banh QQ, Goldsbury JA, Zenger KR, Jerry DR. Domingos JA, et al. PLoS One. 2018 Sep 18;13(9):e0204182. doi: 10.1371/journal.pone.0204182. eCollection 2018. PLoS One. 2018. PMID: 30226860 Free PMC article.
To elucidate whether DNA methylation is involved in sex control of barramundi, a next-generation bisulfite amplicon sequencing approach was used to target 146 CpG sites within proximal promoters and first exons of seven sex-related genes (dmrt1, cyp19a1, amh, foxl2, …
To elucidate whether DNA methylation is involved in sex control of barramundi, a next-generation bisulfite amplicon sequencing approach was …
Transcriptional regulation of CYP19A1 expression in chickens: ESR1, ESR2 and NR5A2 form a functional network.
Guo Y, Cheng L, Li X, Tang S, Zhang X, Gong Y. Guo Y, et al. Gen Comp Endocrinol. 2022 Jan 1;315:113939. doi: 10.1016/j.ygcen.2021.113939. Epub 2021 Oct 27. Gen Comp Endocrinol. 2022. PMID: 34710471
Here, using immunofluorescence and western blotting assay, we first confirmed that CYP19A1 and FOXL2 (Forkheadbox L2) were coexpressed in pre-granulosa cells of female chicken embryonic gonads, while FOXL2 did not affect aromatase expression at embryonic stag …
Here, using immunofluorescence and western blotting assay, we first confirmed that CYP19A1 and FOXL2 (Forkheadbox L2) were coe …
Transcription factors Dmrt1a, Foxl2, and Nr5a1a potentially interact to regulate cyp19a1a transcription in ovarian follicles of ricefield eel (Monopterus albus).
Gan R, Cai J, Sun C, Wang Z, Yang W, Meng F, Zhang L, Zhang W. Gan R, et al. J Steroid Biochem Mol Biol. 2023 Jul;231:106310. doi: 10.1016/j.jsbmb.2023.106310. Epub 2023 Apr 11. J Steroid Biochem Mol Biol. 2023. PMID: 37044240
Aromatase (encoded by Cyp19a1) in the ovarian follicular cells catalyzes the production of estradiol from testosterone, which plays important roles in the ovarian development of vertebrates. ...The expression of dmrt1a, foxl2, and nr5a1a was detected in ovarian foll …
Aromatase (encoded by Cyp19a1) in the ovarian follicular cells catalyzes the production of estradiol from testosterone, which plays i …
Loss- and gain-of-function analyses reveal the essential role of Cyp19a1 in ovarian determination of the red-eared slider turtle.
Shen J, Sun W, Wu K, Zhuang T, Lei J, Ma Q, Xiao L, Ge C. Shen J, et al. Genetics. 2023 May 4;224(1):iyad041. doi: 10.1093/genetics/iyad041. Genetics. 2023. PMID: 36947451
At female-producing temperature, inhibition of aromatase or knockdown of Cyp19a1 in turtle embryos resulted in female-to-male sex reversal, with the formation of a testis-like structure and a male distribution pattern of germ cells, as well as ectopic expression of male-sp …
At female-producing temperature, inhibition of aromatase or knockdown of Cyp19a1 in turtle embryos resulted in female-to-male sex rev …
Sex determination and gonadal sex differentiation in the chicken model.
Hirst CE, Major AT, Smith CA. Hirst CE, et al. Int J Dev Biol. 2018;62(1-2-3):153-166. doi: 10.1387/ijdb.170319cs. Int J Dev Biol. 2018. PMID: 29616724 Free article. Review.
Gonadal DMRT1 is thought to activate other players in testis development, namely SOX9 and AMH, and the recently identified HEMGN gene. DMRT1 also represses ovarian pathway genes, such as FOXL2 and CYP19A1. A lower level of DMRT1 expression in the female gonads is co …
Gonadal DMRT1 is thought to activate other players in testis development, namely SOX9 and AMH, and the recently identified HEMGN gene. DMRT1 …
Synergistic activation of the Mc2r promoter by FOXL2 and NR5A1 in mice.
Yang WH, Gutierrez NM, Wang L, Ellsworth BS, Wang CM. Yang WH, et al. Biol Reprod. 2010 Nov;83(5):842-51. doi: 10.1095/biolreprod.110.085621. Epub 2010 Jul 21. Biol Reprod. 2010. PMID: 20650879 Free PMC article.
Most of the recent studies have heavily focused on the FOXL2 target genes (Star and Cyp19a1) in the ovaries. Hence, it is of importance to search for other downstream targets of FOXL2 and for the possibility of FOXL2 expression in nonovarian tissues. . …
Most of the recent studies have heavily focused on the FOXL2 target genes (Star and Cyp19a1) in the ovaries. Hence, it is of i …
Cooperative effects of oocytes and estrogen on the forkhead box L2 expression in mural granulosa cells in mice.
Ito H, Emori C, Kobayashi M, Maruyama N, Fujii W, Naito K, Sugiura K. Ito H, et al. Sci Rep. 2022 Nov 23;12(1):20158. doi: 10.1038/s41598-022-24680-x. Sci Rep. 2022. PMID: 36424497 Free PMC article.
Forkhead box L2 (FOXL2) plays a critical role in the development and function of mammalian ovaries. ...In the absence of oocytes or estrogen, expression of FOXL2 and its transcriptional targets, Cyp19a1 and Fst mRNA, in MGCs were significantly decreased. ...
Forkhead box L2 (FOXL2) plays a critical role in the development and function of mammalian ovaries. ...In the absence of oocytes or e …
76 results